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Author(s): Antoni Bayés-Genís Added: 3 years ago
The long-awaited 2016 European Society of Cardiology (ESC) guidelines for heart failure (HF)1 provide the large amount of novel research in HF since the previous guidelines published in 2012.2 Here, highlights of the 2016 guidelines are presented. Definition of Heart Failure The main terminology used to describe HF is historically based on measurement of the left ventricular ejection fraction … View more
Author(s): Antonio J Vallejo-Vaz Added: 3 years ago
Heart Failure – A Major Global Health Problem Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality in developed countries and its burden is progressively increasing.1–4 Coronary artery disease (CAD) and other conditions, such as hypertensive heart disease or diabetes mellitus, are rated among the foremost reasons for morbi-mortality worldwide.1–4 In this context,… View more
Author(s): William T Abraham Added: 3 years ago
Hyponatremia is the most common electrolytic abnormality in clinical practice and has a reported incidence of 15–30% in adults.1,2 It is particularly common in heart failure: the Organized Program to Initiate Life Saving Treatment in Patients Hospitalized for Heart Failure (OPTIMIZE-HF) registry recorded that 25.3% of 47,647 heart failure patients had hyponatremia on admission.3 In this registry,… View more
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more
Author(s): Johannes Mair Added: 3 years ago
In 1981, de Bold et al.1 provided the definitive demonstration of the endocrine function of the heart by the description of atrial natriuretic peptide (ANP). This was followed by the identification of brain natriuretic peptide, or B-type natriuretic peptide (BNP), in 1988.2,3 This natriuretic peptide (NP) was originally discovered in the porcine brain, but it is synthesised, stored and released… View more
Author(s): Konstantinos Bratis Added: 3 years ago
Takotsubo syndrome (TTS) is an acute, profound, but reversible heart failure syndrome, usually but not always triggered by physical or emotional stress. To date, the exact pathogenic mechanism of this syndrome remains unclear; however, several hypotheses involving vascular mechanisms (i.e. abnormal coronary epicardial or microvascular vasoreactivity),1-3 endocrine and gender-related mechanisms (i… View more
Author(s): Christian Mueller , Evangelos Giannitsis , James L Januzzi Added: 3 years ago
Improvements in the Early Diagnosis of Acute Myocardial Infarction using a Cardiac Troponin T-high Sensitive Assay In the first talk, Christian Mueller, a Professor at the University Hospital in Basel, discussed the unmet needs of current troponin assays and the improvements made in the early diagnosis of acute myocardial infarction (AMI) using the latest cardiac troponin T-high sensitive (cTnT… View more
Author(s): Miriam Reiter , Tobias Reichlin , Raphael Twerenbold , et al Added: 3 years ago
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Accordingly, prompt identification of patients with AMI is critical, as established therapies exist that are of proven benefit.1,2 More than 15 million patients per year present to emergency departments with symptoms compatible with acute myocardial ischaemia in the US and Europe; only 20–30%, however, are… View more