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Author(s):
Giuseppe Gullace
,
Hassan Khalaf
Added:
3 years ago
The endothelium, which was initially considered to be a semipermeable barrier separating lumen from vessel wall, is now recognised as a complex endocrine organ responsible for a variety of physiological processes vital for vascular homeostasis. These include the regulation of vascular tone, luminal diameter and blood flow; haemostasis and thrombolysis; platelet and leucocyte vessel-wall…
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Author(s):
Muriel Sprynger
Added:
3 years ago
Abstract
Several imaging techniques (such as ultrasounds, computed tomography [CT] scan, magnetic resonance imaging [MRI], positron emission tomography [PET] scan, etc.) can provide interesting information on subclinical atherosclerosis and plaque stability. In fact sonographic imaging techniques can be very useful in this field. All of them have their limitations, but each of them has its own…
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Author(s):
Robert Dalla Pozza
,
Susanne Bechtold
Added:
3 years ago
Atherosclerosis and atherosclerosis-related complications such as coronary, cerebrovascular and peripheral arterial disease show their clinical manifestation in adulthood. However, changes at the endothelial level do not occur suddenly in the elderly, but are the result of a long, on-going, slowly evolving process. We know from autopsy studies that atherosclerotic processes begin in childhood and…
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Author(s):
Cesare Rusconi
Added:
3 years ago
Over the last 30–40 years in most Western countries, for the first time the number of people developing coronary artery disease (CAD) and mortality rates from cardiovascular disease has gradually decreased. This reduction has been mainly achieved using nationwide atherosclerotic risk-factor control programmes. Nevertheless, cardiovascular diseases remain the major cause of premature death in the…
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Author(s):
Rodrigo Alonso
,
Leopoldo Perez de Isla
,
Ovidio Muñiz-Grijalvo
,
et al
Added:
3 years ago
Familial hypercholesterolaemia (FH) is the genetic disorder most commonly associated with elevated LDL cholesterol (LDL-C) levels from birth and with premature atherosclerotic cardiovascular disease (ASCVD).1 It is caused by mutations in genes related to the clearance of LDLs such as LDL receptor (LDLR), apolipoprotein B-100 (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9).2 The…
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Author(s):
Joanne D Schuijf
,
Jeroen J Bax
,
Ernst E van der Wall
Added:
3 years ago
Diabetes is an important risk factor for coronary artery disease (CAD) as reflected by the four-fold greater incidence of CAD in diabetic patients compared with the general population.1 Cardiovascular death is the most common cause of mortality in the type 2 diabetic population and, once diagnosed with CAD, patients with diabetes have a considerably poorer prognosis than their non-diabetic…
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Author(s):
Carolyn M Webb
,
Peter Collins
Added:
3 years ago
Cardiovascular disease (CVD) is the most prevalent non-communicable cause of death worldwide.1 The health and economic implications of caring for a growing ageing population with CVD is enormous. Maintaining a “healthy” elderly population that is mobile and independent with a good quality of life is vital. Testosterone is a sex hormone that is predominant in males, being secreted from the testes…
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Author(s):
Mauricio Wajngarten
Added:
11 months ago
Author(s):
Stefan Möhlenkamp
,
Raimund Erbel
,
Gerd Heusch
Added:
3 years ago
Low to moderate amounts of regular physical activity reduce cardiovascular (CV) risk factor burden, improve morbidity of CV and other chronic diseases and reduce CV mortality.1–6 Aerobic endurance activities such as walking, jogging and running are popular and advocated ways to improve and maintain health across all age groups. Marathon running is an extreme form of such endurance exercise and…
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Myocardial Perfusion Imaging
Author(s):
Carmela Nappi
,
Valeria Gaudieri
,
Alberto Cuocolo
Added:
3 years ago
Article