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Author(s):
Thomas Kahan
Added:
3 years ago
High blood pressure is the major risk factor for disease and premature death worldwide.1 The associations between blood pressure and fatal coronary artery disease and fatal stroke have been well demonstrated.2 Also, associations between blood pressure and morbidity and mortality on specific cardiovascular disease conditions in different age groups, and results concerning the lifetime risk for…
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Author(s):
George Thomas
,
Emmanuel L Bravo
Added:
3 years ago
Distinct hypertensive syndromes causing drug-resistant hypertension are increasingly being recognised. The ability to recognise these disorders has come as a result of a better understanding of their pathogenesis and the availability of sensitive and accurate diagnostic tools. The particular appeal of making the diagnosis centres around the potential curability of the hypertension, with…
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Author(s):
Gurushankar Govindarajan
,
James R Sowers
,
Craig S Stump
Added:
3 years ago
There has been an increase in the prevalence of diabetes mellitus over the past 40 years, both in the US and worldwide. The worldwide prevalence of diabetes in 2000 was approximately 2.8% and is estimated to grow to 4.4% by 2030. This translates to a projected rise of diabetes from 171 million in 2000 to well over 350 million in 2030. The epidemic of diabetes will continue to rise as there is…
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Author(s):
Isla S Mackenzie
,
Thomas M MacDonald
Added:
3 years ago
Hypertension becomes more common with increasing age. As we gradually move towards having a higher proportion of elderly people in the population, greater numbers of octogenarians are being treated for hypertension. In this article we describe the main features of hypertension in the elderly and describe some of the particular issues that affect elderly patients. We also discuss the results of…
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Author(s):
Stefano Taddei
,
Rosa Maria Bruno
Added:
3 years ago
The concept of resistant hypertension (RH) has received great attention in the past years, mainly as a possible target population for innovative therapeutic strategies. An increasing number of original articles and commentaries have focused on the clinical significance, prognosis and treatment of this condition. Thus it is not surprising than even its definition is still a matter of debate,…
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Author(s):
Mauricio Wajngarten
,
Gisele Sampaio Silva
Added:
3 years ago
Stroke is the second most common cause of mortality worldwide and the third most common cause of disability.1 Although there has been a global trend towards a reduction in stroke incidence, prevalence and mortality since the 1990s, the overall stroke burden in terms of absolute number of people affected continues to increase.2 More than 1 million people have a stroke every year in Europe and that…
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Author(s):
Alexandre Persu
,
Fadl Elmula M Fadl Elmula
,
Yu Jin
,
et al
Added:
3 years ago
Renal sympathetic denervation (RDN) has been introduced as a novel approach to treat patients with so-called resistant hypertension.1–3 The first randomised clinical trial showed an impressive 32/12 mmHg fall in blood pressure after six months in the intervention group (n=52) compared to the control group (n=54). However, with the recent publication of the Symplicity HTN-3 study in the US4 the…
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Author(s):
Aarti Thakkar
,
Anandita Agarwala
,
Erin D Michos
Added:
2 years ago
Author(s):
Kashish Goel
,
Colin M Barker
,
JoAnn Lindenfeld
Added:
3 years ago
Heart failure (HF) is a growing epidemic, with an estimated 6.2 million adults (≥20 years) affected between 2013 and 2016 in the US.1 The prevalence is increasing and is expected to reach 8 million by 2030.1 Mitral regurgitation (MR) is common in HF patients, especially in those with ischaemia, left ventricular (LV) dysfunction or dilated cardiomyopathy. MR in the absence of structural…
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