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Author(s): Gustav Steinhoff Added: 3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionise cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction (MI) leads to a net loss of contractile tissue in many patients with coronary artery disease (CAD). Often, this is the beginning of a downward spiral towards congestive… View more
Author(s): Marcus Bracklo , Ulrike Marczak Added: 3 years ago
The recent acquisitions of two leading American reprocessing businesses by leading medical devices manufacturers have relaunched the debate around the reprocessing of medical devices. In 2009, Stryker acquired Ascent and, more recently, Johnson & Johnson acquired SterilMed. This represents a major shift in the strategy of large medical devices companies. In the past, they were very critical of… View more
Author(s): Peter A Meredith Added: 3 years ago
At a time of resource constraints in the healthcare system worldwide, cost issues increasingly influence medication-prescribing habits. For this reason, healthcare providers encourage physicians and pharmacists to use generic drugs, which offer the single advantage of being cheaper than the original proprietary product. Whether this approach is eventually justified with regard to the efficient… View more
Author(s): Olusola A Orimoloye , Albert D Osei , SM Iftekhar Uddin , et al Added: 3 years ago
It often takes time to accumulate enough evidence to deem causal hypotheses plausible truths. Since the introduction of e-cigarettes about a decade ago, studies assessing their potential health effects have resulted in a weak evidence base for causal links to several important clinical outcomes.1 Specifically, according to the National Academies of Science, Engineering, and Medicine’s summary of… View more
Author(s): Alessandro Pingitore , Giorgio Iervasi , Francesca Forini Added: 3 years ago
Cardioprotection includes all methods and mechanisms that lead to the reduction in infarct size, and is thus involved in the evolution of post-ischaemic heart failure (HF). This is a growing research issue since ischaemic heart disease is the leading cause of morbidity and mortality worldwide. A key challenge for these studies is the unravelling of cardioprotection complexities such as the… View more
Author(s): Jean-Luc Vachiéry Added: 3 years ago
Prostacyclins in PAH - Pathobiological Rationale Endothelial dysfunction is the cornerstone event in the pathobiology of pulmonary arterial hypertension (PAH), a rapidly evolving clinical syndrome of dyspnoea and fatigue eventually leading to right ventricular failure and death.1 In the pulmonary vascular bed, endothelial cells are the major source of mediators modulating pulmonary vascular tone… View more