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The Effect of Statins on the Functionality
Author(s): Nilofer Sorathia , Hussein Al-Rubaye , Benham Zal Added: 3 years ago
Statins are most frequently prescribed for the primary prevention of cardiovascular disease due to their lipid-lowering properties. They are known to exert their effect by competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. The reduction in the synthesis of cholesterol induces upregulation of LDL receptors in the liver, resulting in increased clearance and… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Pablo Avanzas Added: 3 years ago
It is a great pleasure for me to introduce the International Society of Cardiovascular Pharmacotherapy (ISCP) section on cardiovascular pharmacotherapy. This issue features a variety of excellent manuscripts on intriguing topics, including the anti-inflammatory effects of curcumin, the effects of statins on T-cell function in acute coronary syndrome in Asian populations, and the cost… View more

Prevention & Chronic Conditions

MI/ACS
The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives
Author(s): Sotirios Tsalamandris , Alexios S Antonopoulos , Evangelos Oikonomou , et al Added: 3 years ago
Diabetes is a multifaceted metabolic disorder affecting the glucose status of the human body. Impaired glucose tolerance and hyperglycaemia are the main clinical and diagnostic features and the result of an absolute or relative insulin deficiency or resistance to its action. Chronic hyperglycaemia associated with diabetes can result in end organ dysfunction and failure which can involve the… View more

Prevention & Chronic Conditions
Anti-inflammatory Treatment and Cardiovascular Outcomes
Author(s): Alberto Lorenzatti Added: 2 years ago

Prevention & Chronic Conditions
Author(s): Ricardo A Perez de la Hoz , Sandra Patricia Swieszkowski , Federico Matias Cintora , et al Added: 3 years ago
The aim of reviewing the neuroendocrine–humoral response in acute coronary syndrome (ACS) is based on the fact that beyond the distinctive thrombotic event that defines acute occlusion of a coronary artery, generically referred to as a plaque accident, it is not an isolated event. It is clear that a series of physiological and physiopathological mechanisms related to stress – before, during and… View more

Prevention & Chronic Conditions

MI/ACS
Author(s): Daniel Alejandro Lerman , Sai Prasad , Nasri Alotti Added: 3 years ago
Progressive thickening of the aortic valve leaflets and narrowing of the aortic annulus leads to increased mechanical stress on the left ventricle and reduces cardiac output, resulting in further complications.1–3 The proportion of the population affected increases as the median age of a country or region rises. Approximately 2–4 % of people aged over 65 will develop calcific aortic stenosis,… View more

Vascular Disease and Surgery

Intervention
Author(s): Gustav Steinhoff Added: 3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionize cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction leads to a net loss of contractile tissue in many patients with coronary artery disease. Often, this is the beginning of a downward spiral towards congestive heart… View more

Vascular Disease and Surgery
Management of Atrial Fibrillation Using Immunoglobulin Free Light Chains, Novel Biomarkers of Inflammation
Author(s): Akira Matsumori Added: 1 year ago

Imaging & Diagnostics

Heart Failure
The Association Between Psoriasis and Cardiovascular Diseases
Author(s): Ahmed Zwain , Mohanad Aldiwani , Hussein Taqi Added: 2 years ago

Prevention & Chronic Conditions
Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence
Author(s): Domenico D’Amario , Stefano Migliaro , Josip A Borovac , et al Added: 3 years ago
The ancient rite of smoking dates back thousands of years, and tobacco smoking has been largely ingrained in our civilization since the arrival of Europeans to the Americas in the 16th century. For a long time, cigarette smoking was perceived as a symbol of wealth, glamour and sophistication, whereas nowadays it is largely recognised as the first preventable or modifiable cause of common diseases… View more

Prevention & Chronic Conditions