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Author(s): PO Collinson Added: 3 years ago
The natriuretic peptides are a family of ring shaped vasoactive hormones showing considerable sequence homology. Four natriuretic peptides have been described, named A-D type (see Figure 1). Of these, commercial immunoassays have been developed for B type natriuretic peptide (BNP) and the N terminus of the prohormone, N terminal pro BNP (NTproBNP). There has been an explosion of clinical studies… View more

Heart Failure

MI/ACS
Author(s): Roland RJ van Kimmenade , James L Januzzi Added: 3 years ago
Heart failure (HF) is currently achieving epidemic proportions, representing the single fastest-growing diagnosis among patients aged >65 years of age and the most common cause for hospitalisation in these patients.1 In addition to having a high incidence and prevalence, HF is associated with substandard clinical outcomes and with high rates of hospitalisation and death.1 Accordingly, great… View more

Heart Failure

MI/ACS
Author(s): Kenneth McDonald , Ulf Dahlström Added: 3 years ago
Despite recent advances in therapy, heart failure (HF) remains a major cardiovascular epidemic worldwide. The increasing prevalence of the syndrome demands further improvement in practice and management to curb the economic and morbidity burden. Current Dilemmas in Heart Failure Diagnosis and Care Heart failure is a condition characterised by non-specific symptoms and unremarkable physical… View more

Heart Failure

MI/ACS
Author(s): Torbjørn Omland Added: 3 years ago
Acute coronary syndromes (ACS) and heart failure (HF) are both associated with complex neurohormonal activation. Commensurate with advances in pharmacological and device therapies for both conditions, the concept of using circulating biomarkers for diagnosis and risk stratification, as well as for targeting and monitoring therapy, has received great attention. Although many novel biomarkers have… View more

Heart Failure

MI/ACS
Author(s): Antonio J Vallejo-Vaz Added: 3 years ago
Heart Failure – A Major Global Health Problem Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality in developed countries and its burden is progressively increasing.1–4 Coronary artery disease (CAD) and other conditions, such as hypertensive heart disease or diabetes mellitus, are rated among the foremost reasons for morbi-mortality worldwide.1–4 In this context,… View more

Imaging & Diagnostics

Heart Failure
Author(s): Thomas Wolber Added: 3 years ago
Coronary artery disease (CAD) is the leading cause of death in adults, accounting for more than 480,000 deaths in the US and 1.95 million deaths in Europe each year. There is considerable interest in early diagnosis of CAD, because obstructive coronary artery disease can exist with minimal or no symptoms and can progress rapidly. In patients with symptoms suggestive of CAD, a variety of tests and… View more

Prevention & Chronic Conditions
Highlights from the ESC Congress 2021
Author(s): Giulia Ferrannini , Gianluigi Savarese Added: 1 year ago

Heart Failure

Electrophysiology & Arrhythmia
Diagnosing Heart Failure – Experience and ‘Best Pathways’
Author(s): Clare Taylor , Richard Hobbs Added: 3 years ago
Heart failure is a complex clinical syndrome that results from a structural or functional cardiac abnormality. The prevalence of heart failure is likely to increase as the population ages and survival rates following myocardial infarction continue to improve.1 Morbidity and mortality rates are significant and relate to high healthcare costs in terms of hospital admissions and long-term care.2… View more

Imaging & Diagnostics

Heart Failure
A Mark Richards
Job title: Director of the Christchurch Heart Institute
Professor A. Mark Richards MD(Otago) PhD(Otago) FRACP is director of the Christchurch Heart Institute. Dr Richards also holds joint appointments at the University of Otago and the National University of Singapore’s Cardiovascular Research Institute. Research interests Neurohormonal physiology and pathophysiology in cardiovascular health and disease Heart Failure Acute Coronary Syndromes… View more
Author(s): Serge Masson , Roberto Latini Added: 3 years ago
Chronic heart failure (HF) is a major cause of death and disability. Predicting patients at risk of death or further cardiovascular events that require more intense monitoring and therapy is clinically challenging. Several factors are associated with increased mortality and morbidity in patients with HF, including age, a history of diabetes mellitus or renal dysfunction, advanced functional… View more

Heart Failure

MI/ACS