Search results
Author(s):
Denise Hilfiker-Kleiner
,
Gerald S Werner
,
Gerd Heusch
Added:
3 years ago
A Cathepsin D-Cleaved 16kDa Form of Prolactin Mediates Postpartum Cardiomyopathy
Hilfiker-Kleiner D, Kaminski K, Podewski E, et al.
Cell, 2007;128(3):589–600
Postpartum cardiomyopathy (PPCM) is a disease of unknown aetiology exposing women to high risk of mortality after delivery. This study shows that female mice with a cardiomyocyte-specific deletion of STAT3 develop PPCM. In these mice,…
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Author(s):
Rick Geoffrion
Added:
3 years ago
Cardiovascular Disease
Cardiovascular disease associated with atherosclerosis is a condition mainly associated with a thickening of the artery wall and the eventual blockage of blood flow in an artery due to fatty deposits and plaque formation. When cardiovascular disease is brought to mind, the heart is what people think of most; however, although the heart is the predominant organ affected by…
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Stavros Stavrakis
Research Area(s) / Expertise:
Job title: Associate Professor of Medicine; Laureate Chair in Molecular Medicine; Vice Chief, Cardiovascular Section
Author
Author(s):
Sven M Francque
Added:
3 years ago
Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver disease in western countries.1,2 It is closely associated with obesity, diabetes, dyslipidaemia and the metabolic syndrome, and shares common risk factors and pathophysiological mechanisms with these entities.2,3 NAFLD can be associated with hepatocellular damage and inflammation and is then called non-alcoholic…
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Author(s):
Farzaneh Dastan
,
Saghar Barati
,
Zargham Hossein Ahmadi
Added:
11 months ago
Author(s):
Andrea Barison
,
Luigi Emilio Pastormerlo
,
Alberto Giannoni
Added:
3 years ago
Among the various cardiovascular diseases, non-ischaemic dilated cardiomyopathy (DCM) represents a major cause of morbidity and mortality.1 DCM is characterised by the presence of left ventricular dilatation and systolic dysfunction in the absence of coronary artery disease or abnormal loading conditions (hypertension, valvular disease).2 It originates from several aetiologies and includes…
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Author(s):
Sreenivasa Rao Kondapally Seshasai
,
Juan Carlos Kaski
Added:
3 years ago
Although the gains of the industrial revolution have transformed human life, they have also left an adverse impact on our health and environment.1 Therefore, factors such as environmental pollution (and pollutants) have lately been the subject of intense scientific investigation.
Traffic noise represents a major environmental burden, which has been suggested to lead to serious cardiovascular…
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Author(s):
Peter Hunold
,
Jörg Barkhausen
Added:
3 years ago
There are many things in life everybody wants more of, and this is particularly true for magnetic resonance imaging (MRI). The major challenge in the daily life of an MRI professional is gaining maximal image signal and contrast in a reasonable amount of time. The application of gadolinium (Gd)-based MR contrast material has offered contrast features in MRI that have been used and appreciated for…
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Author(s):
Barinda Agian Jeffilano
,
Wawaimuli Arozal
,
Ulfa Tri Wahyuni
,
et al
Added:
2 years ago
Author(s):
Morihiro Matsuda
Added:
3 years ago
Background and aims: Obesity-induced chronic low-grade inflammation is causally associated with insulin resistance leading to dyslipidaemia, which is a residual risk for coronary artery disease in patients on statin therapy. The aim of this study is to clarify the impacts of adipocytokines and obesity-associated inflammatory markers on apolipoprotein (apo) A1 and B in patients on statin therapy.
…
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