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TBL1 Suppresses Cardiomyocyte Hypertrophy by Regulating the Interaction Between HDAC3 and GATA4

… Figures & Tables Article TBL1 Suppresses Cardiomyocyte Hypertrophy by Regulating the Interaction Between HDAC3 and … Permissions Views: 38 Likes: 0 Abstract Keywords Cardiac hypertrophy , heart failure , HDAC3 , novel pharmacological … Topic: Heart Failure (Basic), Molecular Cardiology Cardiac hypertrophy is a risk factor for the development of heart …

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A Novel Target Molecule of Nobiletin Derived from Citrus Peels has a Therapeutic Potency Against the Development of Heart Failure

… View PDF Permissions Views: 118 Likes: 0 Abstract Keywords Hypertrophy , heart failure , natural product , Received: 15 … and Cardiomyopathy Introduction and Objectives Maladaptive hypertrophy is being recognized as a critical event during … that a natural compound, curcumin, prevented cardiomyocyte hypertrophy and the development of heart failure in two …

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Analysis of the Effects of EPA and DHA on Cardiomyocyte hypertrophy

… Analysis of the Effects of EPA and DHA on Cardiomyocyte hypertrophy Ayumi Katayama , Masafumi Funamoto , Kana Shimizu … A major morphogenic change in heart failure is the hypertrophy of individual cardiomyocytes. Suppressing cardiomyocytes hypertrophy enables the prevention and treatment of heart …

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Article

The GATA4 Acetylation Site Plays a Key Role in the Development of Cardiomyocyte Hypertrophy

… Site Plays a Key Role in the Development of Cardiomyocyte Hypertrophy Satoshi Shimizu , Yoichi Sunagawa , Kodai Hara , … 0 Abstract Keywords GATA4 acetylation , cardiomyocyte hypertrophy , heart failure , Received: 24 December 2018 … of 3xG4D inhibited phenylephrine-induced cardiomyocyte hypertrophy. To perform a crystal structure analysis, a …

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Article

Hypertensive Heart Disease - Diagnosis, Prognostic Value and Changes During Antihypertensive Treatment, Left Ventricular Structure and Function

… been determined that patients with left ventricular (LV) hypertrophy have increased cardiovascular morbidity and … precision as for aortic valve replacement. Reduction of LV hypertrophy, independent of the simultaneous blood pressure … reduction in cardiovascular mortality if patients with LV hypertrophy were treated to limits of LV mass. Hypertension …

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A PRMT5 Selective Inhibitor EPZ015666 Suppressed TAC-induced Left Ventricular Dysfunction

… Permissions Views: 113 Likes: 0 Abstract Keywords Cardiac hypertrophy , heart failure , cardiomyocyte hypertrophy , arginine methyltransferase 5 , EPZ015666 , transverse aortic constriction (TAC)-induced cardiac hypertrophy , Received: 26 December 2018 Accepted: 26 …

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Histopathological Changes and Clinical Implications in Patients with Hypertrophic Cardiomyopathy

… The histopathological hallmarks of HCM are general myocyte hypertrophy, regions of myocyte disarray, different types of … In the beginning, HCM was described as asymmetrical septal hypertrophy of the left ventricle, but it is now clear that … histopathological hallmarks of HCM with general myocyte hypertrophy, i.e. regions of myocyte disarray, 7 different …

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Article

Hypertrophic Cardiomyopathy in Athletes

… of HCM may be challenging in athletes as pathological hypertrophy of the left ventricle may also mimic physiological left ventricular hypertrophy (LVH) in response to exercise. Differentiation of … heart , hypertrophic cardiomyopathy , left ventricular hypertrophy , sudden cardiac death , Disclosure: The author …

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Article

Role of T1 Mapping in Inherited Cardiomyopathies

… mid-wall LGE in DCM, patchy LGE in areas of hypertrophy in HCM, and global subendocardial LGE in amyloid … as a disease of the cardiac muscle characterised by hypertrophy of the left ventricle in the absence of another … changes within the heart, including cellular disarray, hypertrophy and interstitial fibrosis. These changes lead to …

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Article

A Transcriptional Co-activator, p300 is Involved in the Epigenetic Gene Activation on Hypertrophic Response Gene Promoters in Heart Failure

… of GATA4, as well as for pathological left ventricular hypertrophy (LVH) and the development of heart failure (HF) … and H3K14 in the tail domain increased in cardiomyocyte hypertrophy, western blotting and chromatin- … acetylation of H3K122, H3K9, and H3K14 in cardiomyocyte hypertrophy. The ChIP assay demonstrated that PE increased …

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