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TCT 25: VICTORY Trial: Intravascular Lithotripsy vs Super-High-Pressure Balloons for Calcified Coronary Lesions
Author(s): Matthias Bossard Added: 1 month ago
TCT 2025 - The randomized VICTORY Study finds OCT-guided PCI involving lesion preparation with the OPN super-high-pressure non-compliant balloon is non-inferior to intravascular lithotropsy.Dr Matthias Bossard (Kantonsspital Lucerne, Lucerne, CH) joins us to discuss findings from the VICTORY Trial, a randomized, multicenter, non-inferiority comparison evaluating intravascular lithotripsy versus… View more

Intervention

MI/ACS
PFA Mapping: Essential or Overrated?
Author(s): Devi Nair , Bradley P Knight , Andrea Natale Added: 1 year ago
The role of mapping in pulsed-field ablation (PFA) is a topic of ongoing debate amongst clinicians: is it essential for ensuring successful outcomes, or does it add unnecessary complexity to a procedure designed for precision and simplicity?In this month's episode of Rhythm Interventions Unplugged, host Dr Devi Nair (St Bernards Heart & Vascular, US) is joined by leading electrophysiologists, Dr… View more

Electrophysiology & Arrhythmia
HRS New Policy Statement for Catheter Ablation of AF
Author(s): Kenneth Ellenbogen Added: 1 year ago
A new policy statement released by HRS underscores the importance of continual training and education for electrophysiologists performing catheter ablation of atrial fibrillation (AF).In this short interview, Dr Kenneth Ellenbogen (VCU School of Medicine, US) discusses the key recommendations within this policy statement to ensure a strong electrophysiology base and skillset to achieve the best… View more

Electrophysiology & Arrhythmia
VHPSD versus Conventional Catheter Ablation in AF
Author(s): Giky Karwiky , Mohammad Iqbal , Raymond Pranata Added: 1 year ago
In this episode of the Radcliffe Podcast, we are joined by Dr Raymond Pranata, Dr Mohammad Iqbal and Dr Giky Karwiky (Hasan Sadikin General Hospital, Bandung, Indonesia) as they discuss their recently published systematic review and meta-analysis of very-high-power short-duration ablation as compared to conventional ablation for the treatment of pulmonary vein isolation in atrial fibrillation.13… View more

Electrophysiology & Arrhythmia
EHRA 24: FIH Novel PFA Catheter for PVI
Author(s): Vivek Reddy Added: 1 year ago
EHRA 24 - We interview Dr Vivek Reddy (Icahn School of Medicine at Mount Sinai, US) on a first-in-human clinical trial of a novel conformable "single-shot" pulsed field ablation (PFA) catheter for pulmonary vein isolation (PVI).This single arm trial aimed to assess the safety and efficacy of PVI using an 8Fr PFA catheter (SpherePVI, Affera Inc) in 30 patients across three centers.Interview… View more

Electrophysiology & Arrhythmia
AHA 25: The OCEAN Trial
Author(s): Atul Verma Added: 3 weeks ago
AHA Scientific Sessions 2025 - Dr Atul Verma (McGill University Health Centre, Montreal, CA) joins us to share outcomes from OCEAN (NCT02168829). The prospective, open-label, randomised trial aimed to investigate ongoing oral anticoagulation with rivaroxaban 15 mg daily compared to antiplatelet therapy in patients with clinical stroke risk factors at least one year post-successful catheter… View more

Anticoagulation

Electrophysiology & Arrhythmia
AHA 25 Late-breaking Discussion: The VESALIUS-CV Trial
Author(s): Erin A Bohula , Harriette Van Spall Added: 3 weeks ago
AHA Scientific Sessions 2025 – Late-breaker host Dr Harriette Van Spall (McMaster University, CA) is joined by Dr Erin A Bohula (Brigham & Women's Hospital, US) to discuss the primary results of the VESALIUS-CV trial, a large-scale, phase 3, double-blind, randomised, placebo-controlled study sponsored by Amgen.The VESALIUS-CV trial (NCT03872401) evaluated the impact of evolocumab, a PCSK9… View more

MI/ACS

Prevention & Chronic Conditions
ACC.24: The Embo-Abl Study
Author(s): Kengo Kusano Added: 1 year ago
ACC.24 — We are joined by Dr Kengo Kusano (National Cerebral and Cardiovascular Center, JP) to discuss the findings from the Embo-Abl Study.Embo-Abl is a multicenter prospective randomized study which aims to compare the incidence of periprocedural cerebral embolisms caused by catheter ablation of atrial fibrillation (AF) between cryoballoon and radiofrequency ablation. 230 patients with AF from… View more

Electrophysiology & Arrhythmia
ESC 25: The HI-PRO Trial
Author(s): Gregory Piazza Added: 3 months ago
ESC Congress 2025 - HI-PRO shows apixaban 2.5mg twice daily reduced the risk of symptomatic recurrent venous thromboembolism when compared to placebo at 12 months.Dr Gregory Piazza (Brigham and Women's Hospital, US) joins us to discuss findings from the HI-PRO trial, evaluating extended-duration low-intensity apixaban versus placebo for secondary prevention in high-risk patients with provoked… View more

Anticoagulation

Vascular Disease and Surgery
ESC 25: The KARDIA-3 Study
Author(s): Neha Pagidipati Added: 3 months ago
ESC Congress 2025 - KARDIA 3 finds that a single dose of zilebesiran 300mg reduced office systolic blood pressure at month three compared to placebo, informing the dose, design and patient population for the upcoming zilebesiran phase III Cardiovascular outcomes trial.Dr Neha Pagidipati (Duke University Medical Center, US) joins us to discuss findings from the KARDIA-3 trial, evaluating… View more

Prevention & Chronic Conditions