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Added:
3 years ago
Renal sympathetic denervation (RDN) has been introduced as a novel approach to treat patients with so-called resistant hypertension.1–3 The first randomised clinical trial showed an impressive 32/12 mmHg fall in blood pressure after six months in the intervention group (n=52) compared to the control group (n=54). However, with the recent publication of the Symplicity HTN-3 study in the US4 the…
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Added:
1 year ago
ACC.23/WCC — Principle investigator of YELLOW III, Dr Annapoorna Subhash Kini(Mount Sinai Hospital, US) joins us to talk about the study that assessed the effect of evolocumab (Repatha) on coronary plaque morphology using intravascular imaging and gene expression analysis of peripheral blood mononuclear cells (PBMC) in 140 patients with stable CAD on maximally tolerated statin therapy …
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3 years ago
Clopidogrel is the most widely prescribed P2Y12 inhibitor in the world despite the development of newer and more potent agents.1,2 Clopidogrel is administered as a pro-drug and needs to be metabolised by the cytochrome P450 enzymes (particularly by CYP2C19) in order to have biological activity.3
Patients with loss of function (LOF) variants of the CYP2C19 gene have decreased serum levels of…
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Added:
6 years ago
Expert discussion: The effect of dabigatran in patients suffering myocardial injury after non-cardiac surgery (MANAGE).
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Added:
3 years ago
Coronary artery disease (CAD) is the most common cause of morbidity and premature mortality globally,1 and cardiac autonomic dysfunction is one of the risk factors for CAD.2 Heart rate variability (HRV) is the physiological phenomenon of variation in the time interval between heartbeats and is one of the most promising non-invasive diagnostic methods for assessing autonomic dysfunction.
HRV…
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2 years ago
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12 months ago
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1 year ago
HFSA 22 - Dr James Januzzi (Massachusetts General Hospital, US) outlines the findings of the PROVE-HF study, a trial which aimed to determine the effect of sacubitril/valsartan therapy on cardiac biomarkers in patients with mitral regurgitation in heart failure with reduced ejection fraction.
Questions:
1. What was the ideology behind PROVE-HF?
2. What is the mechanism of action behind…
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Added:
5 years ago
Upcoming webinar
AdaptivCRT™ algorithm for chamber and timing optimisation in CRT devices and the effect in a real-world population
Featuring
Prof. Carina Blomström-Lundqvist, Dr. Maurizio Lunati & Dr Ulrike Neuhold
Click here to see more information and reserve your seat today!
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Added:
3 years ago
Aim: Chronic heart failure (CHF) is a common cause of mortality and morbidity. Obesity influences the CHF development and prognosis. This study was conducted to assess effect of heart failure reversal therapy (HFRT), a combination of panchakarma and allied therapies, on anthropometric parameters in CHF patients.
Methods: This retrospective study was conducted on data of patients who visited…
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