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Research Area(s) / Expertise: Job title: Professor
Professor Keith AA Fox is Duke of Edinburgh Professor of Cardiology at the University of Edinburgh. Previous posts included Assistant Professor of Internal Medicine and Cardiology at Washington University School of Medicine, St Louis, USA; Senior Lecturer in Cardiology and Honorary Consultant Cardiologist at the University of Wales College of Medicine, Cardiff; Head of Division of Medical and… View more
Author(s): Keith AA Fox Added: 3 years ago
Cardiology was never forefront on my mind. I grew up in Central Africa in Zimbabwe where my father was a banker and I went to local schools. I always had an interest in the sciences so during a gap year between school and university I worked in the Queen Elizabeth Hospital in Malawi in the labs and trauma outpatient clinic. This fed my enthusiasm to pursue science and was really quite informative… View more
Author(s): Syed Haseeb Raza Naqvi , Madiha Fatima , Fady Gerges , et al Added: 3 years ago
The current coronavirus disease 2019 (COVID-19) outbreak is more than a health crisis, and its impact on the management of other diseases of various specialties is one of the greatest challenges facing healthcare professionals. Health associations worldwide are now recommending dealing with emergencies only, utilising telemedicine and providing ambulatory facilities, where available, for non… View more
Author(s): Harvey D White , Derek P Chew Added: 3 years ago
The cumulative evidence base informing almost every aspect of myocardial infarction acute coronary syndrome (ACS) care is expansive and has been associated with a decline in the rate of mortality. Within the context of current-era clinical trials of ST-segment-elevation myocardial infarction, 30-day mortality rates of 4–5% have now been reported for high-risk individuals,1,2 with similar rates… View more
Author(s): Wolfgang Koenig Added: 3 years ago
The notion that atherosclerosis carries features of an inflammatory disease has existed for quite some time. As early as 1856, Rudolf Virchow in his Textbook on Pathology mentioned the term “coronaritis”. Almost 150 years later, following the elucidation of major cardiovascular risk factors in the 1950s Framingham Study, Russell Ross entitled his 1999 review on mechanisms of atherosclerosis … View more
Author(s): Ricardo A Perez de la Hoz , Sandra Patricia Swieszkowski , Federico Matias Cintora , et al Added: 3 years ago
The aim of reviewing the neuroendocrine–humoral response in acute coronary syndrome (ACS) is based on the fact that beyond the distinctive thrombotic event that defines acute occlusion of a coronary artery, generically referred to as a plaque accident, it is not an isolated event. It is clear that a series of physiological and physiopathological mechanisms related to stress – before, during and… View more
Author(s): Jason M Tarkin , Juan Carlos Kaski Added: 3 years ago
Stable angina pectoris is the most prevalent clinical manifestation of coronary heart disease. While the overall prognosis in patients with stable angina is good, with a low yearly event rate of ~1–2 %,1 for many, adequate symptom control can be difficult to achieve, leading to significantly impaired quality of life. The traditional approach to the pharmacological management of stable angina, as… View more
Author(s): Ronald K Binder , Ahmed A Khattab Added: 3 years ago
The treatment of acute myocardial infarction (AMI) has substantially improved in recent decades. Thrombolysis, the former first-line therapy, which is inexpensive and may be administered without noteworthy delay in primary care or pre-hospital settings, has been replaced by primary percutaneous coronary intervention (PCI) despite the inherent delay of transfering patients to a cardiac… View more
Author(s): Daniel Alejandro Lerman , Nasri Alotti , Kiddy Levente Ume , et al Added: 3 years ago
Acute myocardial infarction (AMI) is still a major public health problem worldwide, causing high rates of morbidity and mortality. In the United States, nearly one million patients suffer from AMI each year.1 In the UK, around 80,000 people died from coronary heart disease (CHD) in 2010.2 The current approach to the treatment of myocardial infarction involves early revascularisation with… View more
Author(s): Joakim Alfredsson , Eva Swahn Added: 3 years ago
Cardiovascular diseases are the leading cause of death in industrialised countries; among these, coronary artery disease (CAD) is the most prevalent and is associated not only with high mortality but also with substantial morbidity. Acute manifestations of CAD are ST-elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), unstable angina pectoris (UAP) and sudden ischaemic death.1 Due to the… View more