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Author(s): Philip A Poole-Wilson Added: 3 years ago
Introduction Coronary heart disease (CHD), due to atheromatous obstruction of coronary arteries, is the most common form of heart disease. The atheroma forms and accumulates in the wall of the coronary artery (coronary atherosclerosis) beginning at an early age. The disease is thought to be initiated by damage to the endothelium - the inner lining of the vessel wall - as a consequence of a… View more

Prevention & Chronic Conditions
Author(s): Philip A Poole-Wilson Added: 3 years ago
Introduction Coronary heart disease (CHD), due to atheromatous obstruction of coronary arteries, is the most common form of heart disease. The atheroma forms and accumulates in the wall of the coronary artery (coronary atherosclerosis) beginning at an early age. The disease is thought to be initiated by damage to the endothelium - the inner lining of the vessel wall - as a consequence of a… View more

Prevention & Chronic Conditions

Heterogeneous Populations
Nicorandil and Long-acting Nitrates: Vasodilator Therapies for the Management of Chronic Stable Angina Pectoris
Author(s): Jason M Tarkin , Juan Carlos Kaski Added: 3 years ago
Stable angina pectoris is the most prevalent clinical manifestation of coronary heart disease. While the overall prognosis in patients with stable angina is good, with a low yearly event rate of ~1–2 %,1 for many, adequate symptom control can be difficult to achieve, leading to significantly impaired quality of life. The traditional approach to the pharmacological management of stable angina, as… View more

Prevention & Chronic Conditions
Author(s): Giacinta Guarini , Alda Huqi , Doralisa Morrone , et al Added: 3 years ago
Although cardiovascular mortality has declined progressively in developed countries, ischaemic heart disease (IHD) and chronic stable angina cause a worse prognosis and poor quality of life and can dramatically increase healthcare costs.1–4 Traditionally, chronic stable angina has been interpreted as reversible episodes of myocardial ischaemia due to the presence of coronary artery disease… View more

Prevention & Chronic Conditions

MI/ACS
Stable Angina Medical Therapy
Author(s): Talla A Rousan , Udho Thadani Added: 3 years ago
Background Definition of Stable Angina Angina pectoris was first defined by William Heberden in 1768. He described it as a smothering sensation or tightness across the front of the chest which may radiate to the left arm or to both arms as well as the jaw or back. It is usually triggered by exercise or emotional stress and it may be aggravated by the ingestion of a heavy meal.1 The pain usually… View more

Standards & Guidelines

Prevention & Chronic Conditions
Management of Refractory Angina Pectoris
Author(s): Kevin Cheng , Paul Sainsbury , Michael Fisher , et al Added: 3 years ago
Refractory angina (RA) is conventionally defined as a chronic condition (≥3 months in duration) characterised by angina in the setting of coronary artery disease (CAD), which cannot be controlled by a combination of optimal medical therapy, angioplasty or bypass surgery, and where reversible myocardial ischaemia has been clinically established to be the cause of the symptoms.1 In clinical… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Santo Dellegrottaglie , Pierluigi Costanzo , Stefania Paolillo , et al Added: 3 years ago
In Europe, subjects >65 years of age currently constitute 17% of the entire population, with some variations between countries (see Figure 1).1 More importantly, as a consequence of the ageing population, elderly subjects are expected to account for 30% of the European population by 2050. Currently, cardiovascular disease is the major cause of death in Europe (~20% of all causes) and more than… View more

Imaging & Diagnostics
AutocathFFR System Outcomes Comparable to Wire-Based FFR
Author(s): Hector M Garcia-Garcia Added: 2 years ago
In this video from CRT 2022's late-breaking trials, Dr Hector M Garcia-Garcia (MedStar Washington Hospital Center, Washington DC, US) discusses the technology behind the hands-free AutocathFFR System, an AI-based method of angiography imaging-derived FFR Technology for coronary artery disease revascularization. Dr Garcia-Garcia reveals that the outcomes of Angiographic-derived FFR were comparable… View more

Digital Health

MI/ACS
Author(s): Margaret McEntegart , Keith G Oldroyd Added: 3 years ago
There has been extensive discussion and debate in terms of the outcome of the recent landmark coronary revascularisation trials and their implications for the future management of chronic stable angina (CSA) and prognostically significant coronary artery disease (CAD). While the Clinical Outcomes Utilizing Revascularisation and Aggressive Drug Evaluation (COURAGE) trial questioned the added… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Kirsten Tolstrup Added: 3 years ago
Ischaemic heart disease is the leading single cause of death in the US and elsewhere, and a major health problem worldwide.1 The direct cost of hospitalisations for ischaemic heart disease in the US alone is enormous and amounts to more than US$15 billion. Consequently, it is very important to facilitate more definitive ischaemia evaluation while avoiding unnecessary hospital admissions of non… View more

MI/ACS