Filters
Close
ADDED DATE
Added date
AUTHOR Please select
TOPICS Please select
WATCH / LISTEN / READ TIME
Author(s): Kreton Mavromatis , William E Boden Added: 3 years ago
Defining the best management strategies for patients with stable ischaemic heart disease (SIHD) has been the subject of scientific study for nearly 50 years since the advent of coronary artery bypass grafting (CABG) surgery by Favaloro in 1967 and, a decade later, the development of percutaneous coronary intervention (PCI) by Gruentzig in 1977.1,2 Randomised controlled trials of CABG surgery… View more
Research Area(s) / Expertise: Job title: Professor of Medicine
Dr. William E. Boden is Professor of Medicine at Boston University School of Medicine and Lecturer in Medicine, Harvard Medical School, in Boston, Massachusetts. In July 2016, Dr. Boden returned to the VA Boston Healthcare System to assume new duties as the Physician Research Lead for the New England VA Healthcare System and as the Scientific Director of the Clinical Trials Network, which is… View more
Author(s): Margaret McEntegart , Keith G Oldroyd Added: 3 years ago
There has been extensive discussion and debate in terms of the outcome of the recent landmark coronary revascularisation trials and their implications for the future management of chronic stable angina (CSA) and prognostically significant coronary artery disease (CAD). While the Clinical Outcomes Utilizing Revascularisation and Aggressive Drug Evaluation (COURAGE) trial questioned the added… View more
Author(s): Maria Chiara Scali , Doralisa Morrone , Mario Marzilli Added: 3 years ago
As coronary angiography is of limited value in defining the functional significance of a stenosis, the timely article by Balanescu in this issue of European Cardiology Review rationally proposes to integrate the anatomic information with a functional assessment, either by measuring coronary flow reserve (CFR) or intracoronary artery pressure with fractional flow reserve (FFR). CFR measurements… View more
Author(s): Dimitrios Bliagos , Ajay J Kirtane , Jeffrey W Moses Added: 3 years ago
Worldwide, it is estimated that the total number of people with diabetes will increase from 171 million in 2000 to 366 million in 2030.1 In the US, a total of 23.6 million people have diabetes, representing 7.8% of the population, and the prevalence of diabetes is on the rise, due to an increasingly sedentary lifestyle, increasing obesity and an ageing population. These statistics do not account… View more
Author(s): Alberto Corsini Added: 3 years ago
Premise Evidence spanning from the pathogenesis of atherosclerosis to epidemiological studies consistently support the direct association of elevated plasma low-density lipoprotein-cholesterol (LDL-C) with the increased risk of cardiovascular disease (CVD). Meta-analysis of 14 trials of statin therapy, with more than 90,000 participants, has shown that each 1mmol/l (39mg/dl) of LDL-C reduction… View more
Author(s): Serban Balanescu Added: 3 years ago
Coronary artery disease (CAD) due to atherosclerosis is a major cause of morbidity and mortality. Early prevention of atherothrombotic disease with a healthy lifestyle (diet, exercise, optimal body weight and no smoking) is considered the best method of “treating” CAD, although increasing age remains associated with significant cardiovascular events. When coronary atherothrombotic disease… View more