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Author(s): Željko Reiner Added: 3 years ago
Coronary heart disease (CHD) is one of the most important cardiovascular diseases and is, together with acute myocardial infarction and ischaemic stroke, the leading cause of death and disease burden in Europe. Over the past two decades death rates from these diseases have been falling in most northern and western European countries but rising rapidly in most eastern European countries. However,… View more

Prevention & Chronic Conditions
Author(s): Maurice Beghetti Added: 3 years ago
Congenital heart diseases (CHDs) are among the most common congenital malformations at birth, with an incidence of 8/1,000 live births. These defects are characterised by a heterogeneous group of abnormal communications and connections between the cardiac chambers and vessels with different haemodynamic consequences and, hence, varying need for follow-up and interventions. The most common forms… View more

Prevention & Chronic Conditions
Atrial Fibrillation in Congenital Heart Disease
Author(s): Irene Martín de Miguel , Pablo Ávila Added: 3 years ago

Heterogeneous Populations

Electrophysiology & Arrhythmia
Findings from an Apolipoprotein B-Based Genetic Analysis
Added: 2 months ago Source:  Radcliffe Cardiology, Greg Guillory
In a study published in the Journal of the American College of Cardiology (JACC), Dr Elias Björnson and his colleagues demonstrated that lipoprotein(a) (Lp(a)) is approximately six times more atherogenic than low-density lipoprotein (LDL) per particle.Lp(a) is a lipoprotein particle that has long been recognised as a causal factor for coronary heart disease (CHD). However, until recently, its… View more
Author(s): Birna Bjarnason-Wehrens , Sandra Schmitz , Sigrid Dordel Added: 3 years ago
Congenital malformations of the heart and vessels occur in five to nine per 1,000 live births.1,2 Some of these malformations (10–15%) do not require correction. Between 70 and 80% of defects can be corrected, and an increasing number of therapeutic procedures can be performed by interventional catheterisation techniques, avoiding the need for open heart surgery.1 Definitive therapeutic… View more

Heterogeneous Populations
Author(s): Alberto Corsini Added: 3 years ago
Premise Evidence spanning from the pathogenesis of atherosclerosis to epidemiological studies consistently support the direct association of elevated plasma low-density lipoprotein-cholesterol (LDL-C) with the increased risk of cardiovascular disease (CVD). Meta-analysis of 14 trials of statin therapy, with more than 90,000 participants, has shown that each 1mmol/l (39mg/dl) of LDL-C reduction… View more

Prevention & Chronic Conditions
Low Density Lipoprotein Cholesterol and Coronary Heart Disease - Lower is Better
Author(s): Hans-Willi Breuer Added: 3 years ago
Epidemiology has repeatedly shown that elevated levels of cholesterol play a key role in the development of atherosclerotic disease. In particular, low density lipoprotein (LDL) cholesterol has been strongly associated with coronary heart disease (CHD) risk.1-5 Lowering LDL cholesterol reduces the incidence of atherosclerotic disease, irrespective of how the reduction is achieved. The efficacy of… View more

Prevention & Chronic Conditions
Influence of Combined Therapy on Inflammatory State and Pro-inflammatory Cytokines in Patients with Coronary Artery Disease and Metabolic Syndrome
Author(s): J Uzokov , A Alyavi , B Alyavi , et al Added: 3 years ago
Background and aims: The aim of the study was to investigate the influence of combined lipid lowering therapy with rosuvastatin and ezetimibe on lipid profile, inflammatory state and pro-inflammatory cytokines in dyslipidaemic patients with coronary heart disease (CHD) and metabolic syndrome (MS). Material and methods: 128 patients with CHD and MS were randomly divided into two groups of 64. The… View more

Prevention & Chronic Conditions
Author(s): Hans-Willi Breuer Added: 3 years ago
Abstract Studies have consistently shown that coronary heart disease (CHD) risk is correlated closely with low density lipoprotein (LDL) cholesterol levels. The lower the LDL cholesterol, the lower the cardiovascular (CV) risk; however, there is a question over how much LDL cholesterol lowering is low enough and what supporting evidence there is for this. This article reviews recent evidence in… View more

Prevention & Chronic Conditions
Author(s): Mario Petretta , Carmela Nappi , Alberto Cuocolo Added: 3 years ago
The application of nuclear medicine techniques to cardiology is based on the identification of the functional consequences of coronary stenoses, i.e. of myocardial ischaemia. In nuclear cardiology, the evaluation of myocardial perfusion with single-photon-emission computed tomography (SPECT) is the most commonly performed procedure. The SPECT study is currently performed with electrocardiogram … View more

Imaging & Diagnostics