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Author(s):
Dennis V Cokkinos
,
Christos Belogianneas
Added:
3 years ago
The term cardiac remodelling (REM) is used to define changes that produce geometrical rearrangement of the normal structures of the heart, together with complex biological and molecular alterations. REM affects the heart at the level of the cardiomyocyte, the blood vessels and the extracellular matrix. Proliferation of the latter, resulting in fibrosis, is one of the hallmarks of pathological REM…
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Author(s):
Gustav Steinhoff
Added:
3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionize cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction leads to a net loss of contractile tissue in many patients with coronary artery disease. Often, this is the beginning of a downward spiral towards congestive heart…
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Author(s):
Andrea Barison
,
Luigi Emilio Pastormerlo
,
Alberto Giannoni
Added:
3 years ago
Among the various cardiovascular diseases, non-ischaemic dilated cardiomyopathy (DCM) represents a major cause of morbidity and mortality.1 DCM is characterised by the presence of left ventricular dilatation and systolic dysfunction in the absence of coronary artery disease or abnormal loading conditions (hypertension, valvular disease).2 It originates from several aetiologies and includes…
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Author(s):
Christos-Konstantinos Antoniou
,
Panagiota Manolakou
,
Nikolaos Magkas
,
et al
Added:
3 years ago
Cardiac resynchronisation therapy (CRT) has been a cornerstone in the treatment of select advanced heart failure cases since its introduction to our armamentarium in the early 2000s.1 Indeed, 30–60% of advanced heart failure patients exhibit evidence of dyssynchrony, when defined electrocardiographically or mechanically.2–4 The latter is a consequence of the former. CRT has several unique…
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Author(s):
José PS Henriques
Added:
3 years ago
Despite considerable improvements in the treatment of acute ST elevation myocardial infarction (STEMI), outcomes have predominantly improved in STEMI patients without cardiogenic shock (CS). Nevertheless, cardiogenic shock occurs in approximately 7–10% of STEMI patients and is the leading cause of death for hospitalised patients. In-hospital mortality rates of STEMI complicated by CS are around…
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Author(s):
Dan Wichterle
Added:
3 years ago
Myocardial infarction (MI) is associated with acute risk of early malignant arrhythmias that can be easily treated during in-hospital intensive care by defibrillation, adjuvant antiarrhythmic therapy or even catheter ablation in resistant cases. Indeed, such management resulted in substantial improvement in MI survival rate. Despite the implementation of primary percutaneous coronary…
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Author(s):
David Antoniucci
Added:
3 years ago
In the setting of acute myocardial infarction (AMI), spontaneous and percutaneous coronary intervention (PCI)-related embolisation results in a decreased efficacy of mechanical reperfusion and myocardial salvage. Direct stenting without predilation may decrease embolisation and the incidence of the no-reflow phenomenon.1,2 More specific approaches to the problem of microvessel embolisation during…
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Abortion of Acute Myocardial Infarction - The Best Possible Achievement of Reperfusion Therapy
Author(s):
Roberto Sciagrà
Added:
3 years ago
Article
Author(s):
Lee Chang
,
Robert Yeh
Added:
3 years ago
Cardiogenic shock is the leading cause of death in patients with acute ST-elevation myocardial infarction (STEMI). Characterised by a state of low cardiac output leading to end-organ hypoperfusion, cardiogenic shock complicates approximately 5–8 % of STEMIs and is associated with a mortality rate approaching 50 percent.1–3 Prompt recognition and therapeutic intervention for cardiogenic shock due…
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