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Author(s): Kazuma Ohyama , Yasuharu Matsumoto , Hiroaki Shimokawa Added: 3 years ago
Coronary Artery Spasm and Adventitial Inflammation Coronary artery spasm plays an important role in the pathogenesis of a wide range of ischaemic heart disease, not only in variant angina, but also in other forms of angina pectoris and myocardial infarction.1,2 Recent studies have demonstrated that coronary spasm is also as frequently noted in European people as in Asian people.3 We have… View more
Author(s): Sana Amraoui , Ghoufrane Tlili , Elif Hindié , et al Added: 3 years ago
With ageing of the general population and broadening indications, the number of pacemaker recipients is steadily increasing. The incidence of cardiac implantable electronic device (CIED) infection, a dreaded major complication, is also rising.1 The diagnosis is based on the presence of an abscessed pocket, cutaneous breakthrough of the pulse generator or vegetations attached to the pacemaker lead… View more
Author(s): Alexandros Protonotarios , Perry Elliott Added: 3 years ago
Until the 20th century, conventional medicine relied almost exclusively on observable characteristics to classify and treat human disease.1 Even in the modern era, physicians define diseases using phenotypic similarities and employ relatively simple algorithms to interpret diagnostic tools and plan treatment. The advent of low-cost genetic sequencing and its introduction into clinical care… View more
Author(s): W Kevin Tsai , Kathleen M Holohan , Kim Allan Williams Added: 3 years ago
Coronary artery disease (CAD) represents a tremendous financial and health burden as the leading cause of death in the US.1 Acute coronary syndrome and its subsequent manifestations, including heart failure and need for cardiac transplantation, are associated with significant morbidity and mortality. Hypertension, dyslipidemia, tobacco abuse, diabetes, chronic kidney disease, and family history… View more
Author(s): Nagara Tamaki , Yuji Kuge , Keiichiro Yoshinaga Added: 3 years ago
The heart requires a high rate of oxygen uptake to maintain mechanical function in order to provide sufficient energy to balance the requirement of the mechanical function. Oxygen consumption increases in almost direct ratio to the increased workload; when the oxygen supply is inadequate for the demand, reversible or irreversible metabolic changes may occur. Such an imbalance is most often… View more
Author(s): MT Bajén , J Martin-Comin Added: 3 years ago
During the last few years we have been facing a revolution in the field of cardioimaging for both diagnostic and short- and long-term prognostic purposes. The introduction of multislice computed tomography (CT) in clinical practice has allowed us to carry out non-invasive coronariography or, when performed without contrast agents, the imaging of coronary artery calcification. Arteriosclerosis can… View more