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Author(s):
Bruno Scheller
Added:
2 years ago
In this video, Professor Bruno Scheller (Saarland University, Saarbrücken, DE) sits down to discuss the one-year angiographic outcomes of two parallel randomized trials investigating the effectiveness off sirolimus-coated and paclitaxel-coated DCB's in the treatment of coronary in-stent restenosis. Findings suggest comparable outcomes in both devices.
Discussion points:
1. Importance of this…
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Author(s):
Dae-Hyun Lee
,
José M de la Torre Hernández
Added:
3 years ago
When Andreas Grüntzig introduced balloon coronary angioplasty in 1977 it represented the first alternative to coronary artery bypass graft surgery. However, balloon dilatation had inherent limitations – including elastic recoil and vessel closure in the acute phase, as well as negative remodelling and restenosis in the late phase – which limited its applicability and further expansion. In the…
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Author(s):
Tamara García Camarero
,
José M de la Torre Hernández
Added:
3 years ago
The use of dual antiplatelet therapy (DAPT) after stent implantation in a percutaneous coronary intervention (PCI) is the standard treatment. The first randomised controlled trial (RCT) to establish the superiority of DAPT versus oral anticoagulant treatment among patients undergoing PCI was the Intracoronary Stenting and Antithrombotic Regimen (ISAR) trial, published in 1996.1 Since then, more…
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Author(s):
Torsten Heilmann
,
Christian Richter
,
Heiko Noack
,
et al
Added:
3 years ago
Drug-coated balloons (DCBs) are a nascent technology gaining a lot of attention among cardiologists and angiologists worldwide. As opposed to drug-eluting stents (DES) they allow intraluminal drug application to diseased arterial tissue without leaving an implant such as a metal scaffold behind. This may be beneficial where a stent is already in place or where stenting is problematic due to…
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Author(s):
Diego Penela
,
Maríbel Diaz-Ricart
,
Magda Heras
Added:
3 years ago
The usual underlying mechanism of acute coronary syndromes (ACSs) is a thrombotic event caused by the rupture or erosion of an atherosclerotic plaque. In this scenario, platelets and thrombin are key players. Thus, understanding the physiopathology of platelet activation is of paramount importance in the treatment of acute coronary ischaemia. There is ample evidence showing that adequate…
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Author(s):
Bruno Scheller
,
Bodo Cremers
,
Stephanie Schmitmeier
,
et al
Added:
3 years ago
Coronary angioplasty was introduced to clinical practice by Andreas Grüntzig in 1977.1 In the coronary field, the most important improvement in angioplasty has been achieved with the introduction of stents. A significant proportion of the complex modern coronary interventional techniques rely on stenting. Stenting overcomes recoil and dissections but not restenosis due to neointimal proliferation…
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Author(s):
Gerald V Naccarelli
,
Deborah L Wolbrette
,
Soraya Samii
,
et al
Added:
3 years ago
Currently available antiarrhythmic drugs for the treatment of atrial fibrillation are limited in their efficacy and have potential for adverse effects, including torsade de pointes. With the aging of the population, the incidence of atrial fibrillation will double in frequency over the next 15 years. Thus, more effective and safer antiarrhythmic drugs for the treatment of atrial fibrillation are…
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Author(s):
Renata Cífková
Added:
3 years ago
Hypertension is the most prevalent cardiovascular disease affecting 20–50 % of the adult population.1 Elevated blood pressure has been identified as a risk factor for coronary heart disease (CHD), heart failure, stroke, peripheral arterial disease, renal failure and atrial fibrillation both in men and women in a large number of epidemiological studies.2–4 So far, the largest meta-analysis of…
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Author(s):
Mikhail Kosiborod
Added:
5 years ago
Mikhail Kosiborod discusses the CVD-REAL 2 study - Lower Risk of Cardiovascular Events and Death Associated With Initiation of SGLT-2 Inhibitors Versus Other Glucose Lowering Drugs.
Filmed on-site at the American College of Cardiology congress 2018 in Orlando, USA.
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Author(s):
Jose L Merino
,
José López-Sendón
Added:
3 years ago
Atrial fibrillation (AF) is the most frequent sustained arrhythmia. The estimation is that five million people suffer the disease in Europe,1 although this number may be even higher because many AF episodes are silent but still associated with a risk of complications.2–4 AF prevalence is increasing in developed countries in part due to the progressive increase in the mean age of the western…
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