The cardiology community has been deeply saddened by the unexpected passing of Prof Amir Lerman, Director of the Cardiovascular Research Center at Mayo Clinic, on 23 February 2026.
Prof Lerman was a pioneer in cardiovascular medicine and a creative thinker whose work in the field of coronary physiology and endothelial function has contributed substantially to the understanding of microvascular angina and its treatment. At the Center for Coronary Physiology and Imaging, part of Mayo Clinic’s Cardiac Catheterization Laboratory, Prof Lerman carried out groundbreaking research in his field of interest and generated vital scientific publications that informed diagnostic strategies and treatments for ischemic heart disease, particularly coronary microvascular dysfunction. He trained and mentored hosts of younger physicians who are now key opinion leaders worldwide and attest to Amir’s passion for teaching and research.
Amir Lerman was a scientist, an innovator and a charismatic leader. I fondly remember meeting him on several occasions to discuss ways of improving our understanding of diseases affecting the coronary microcirculation. He was always available to friends and colleagues, ready to listen and provide sound advice, and generously contributed his knowledge and expertise as an editorial board member of European Cardiology Review.
A very important aspect of Prof Lerman’s work has been the impact that his translational work has had on clinicians and patients the world over. Unfortunately, he leaves us far too early, when he was still able to contribute novel research ideas and incomparable clinical expertise. However, his legacy will continue for years to come and his ideals will become reality through the work of generations of physicians and scientists that he so brilliantly educated and inspired during his accomplished medical life. Our thoughts at this extremely sad time are with Prof Lerman’s family.
Prof Juan Carlos Kaski
Editor-in-Chief, European Cardiology Review, on behalf of the European Cardiology Review team.